Global
About

Committed to the development
of innovative single domain antibody drugs

About Novamab
Committed to becoming the world's leading R&D enterprise of innovative single domain antibody drugs

Novamab is a clinical-stage biotech company dedicated to creating life-changing therapies for patients through innovative VHH technology. We take pride in our highly differentiated and innovative product pipeline, which targets high-potential markets such as asthma, chronic obstructive pulmonary disease (COPD), and inflammatory bowel disease (IBD).

Our most advanced project, an inhaled IL-4R VHH, has progressed to Phase II clinical trials, while our inhaled TSLP VHH is preparing to enter Phase IB proof-of-concept studies. Additionally, we are actively developing several bispecific and oral VHH antibody products aimed at treating inflammatory bowel disease (IBD).

2017
Novamab was founded
60+
Number of employees
3000m2
R&D and production base
500L
GMP workshop for VHH antibody production using Pichia pastoris
About Novamab
Mission&Vision
Mission
Develop life-changing therapeutics for patients, through innovative variable domain of the heavy chain of heavy-chain antibody(VHH)drug research and development and aim to improve efficacy and convenience
Vision
To be a world-leading innovator in VHH therapeutics, pioneering inhaled antibody delivery
About Novamab
Company philosophy

The company concept can be started from the company name. The word nova in Novamab comes from Latin, meaning new, meaning "new". Mab is the abbreviation of monoclonal antibody, so Novamab means new antibody, while the development of VHH antibody has only been more than 20 years, and it is also a new antibody in the field of antibody research and development, so the two correspond to each other.


The "Y" shape in the company's icon represents the structural shape of the VHH antibody that lacks the light chain, and echoes with the VHH antibody again; In addition, the circular part of the icon is similar to a shield, indicating our desire and determination to defend human health, while the stars symbolize our good expectations for VHH antibody and ourselves. We hope that camel (camel and Luo) antibody can become a new star in the field of antibody medicine and start human future health.

About Novamab
Founder
Dr. Yakun Wan
Founder, Chairman and CEO

Dr. Yakun Wan, founder and CEO of Novamab, has 19 years of VHH antibody research experience and is a leading figure in the field. He previously worked at the Shanghai Institute of Pharmaceutical Research, Chinese Academy of Sciences, and Southeast University. Dr. Wan also conducted postdoctoral research at the University of Texas at Austin, Baylor College of Medicine, and the American Institute of Systems Biology.

Dr. Wan has been honored with several awards, such as the "Hundred Talents Plan" by Shanghai Institute of Medicine, the Six Talent Peak Plans by Jiangsu Province, the "High-level Creative Talents Plan" by the Ministry of Education, and the "New Century Excellent Talents" award. He was also acknowledged as an "Outstanding Innovation and Entrepreneurship Talent" in 2021 and a "Pudong New Area Pearl Talent Leader" in 2024. Under his guidance, Novamab was recognized as one of China's top 50 innovative pharmaceutical enterprises in 2020 and a top 100 innovative seed enterprise in 2022, specialized and sophisticated enterprises that produce new and unique products in 2022.

Dr. Wan has authored over 70 scientific papers, with over 50 as first or corresponding author in SCI-indexed journals. He holds over 120 invention patents, 45 of which are authorized, and has led projects funded by Shanghai Biopharmaceutical Innovation and Development Project the Shanghai Science and Technology Innovation Fund and the National Natural Science Foundation, among others.

Dr. Wan founded China's first VHH antibody R&D team in drug development, partnering with top pharmaceutical firms to progress several products to clinical phases. Novamab, with a complete R&D, pilot testing, and GMP production system, is uniquely positioned to handle full-process VHH antibody development in China. The 500L Pichia pastoris GMP pilot production workshop fills a significant industry void. Dr. Wan's team created the world's first inhaled VHH antibody drugs, LQ036 and LQ043H, targeting lL-4Rα and TSLP, respectively. These drugs are intended for patients with moderate-to-severe asthma, providing rapid local effects and low toxicity.